Blood-Based Assays to Predict Response to Combination Checkpoint Blockade, High dose interleukin 2 (HDIL-2) in Melanoma
November 8, Boulder, Colorado…Three studies involving the development and validation of Biodesix’ blood-based proteomic tests, to aid in patient selection or predicting outcomes in the use of immunotherapies, will be presented this week at SITC’s 31st Annual Meeting.
Oral Poster Presentation:
Date and Time: Saturday, November 12, 12:20-12:30 p.m. EDT
Abstract Title: A test identifying advanced melanoma patients with long survival outcomes on nivolumab shows potential for selection for benefit from combination checkpoint blockade
Location: Prince George’s Exhibition Hall AB, in the presentation area in the far back right of the hall
Presenting Author: Jeffrey Weber, M.D. Ph.D – New York University/Langone Medical Center
Additional Authors: Mario Sznol, Harriet Kluger, Ruth Halaban, Heinrich Roder, Joanna Roder, Senait Asmellash, Arni Steingrimsson, Shauna Blackmon, Ryan Sullivan
Poster Presentation:
Date and Time: Saturday, November 12 12:00 p.m. – 1:00 p.m.; Saturday, November 12 6:45 – 8:00 p.m. EDT
Title: Application of a test developed for prediction of response to high dose interleukin-2 (HDIL-2) and the BDX008 test for prediction of outcomes following checkpoint inhibitors to cohorts of patients treated with HDIL-2 or nivolumab
Poster Number/Location: 106
Authors:
Ryan J. Sullivan, Theodore Logan, Nikhil I. Khushalani, Kim Margolin, Henry Koon, Thomas Olencki, Thomas Hutson, Brendan Curti, Joanna Roder, Shauna Blackmon, Heinrich Roder, John Stewart, Asim Amin, Marc Ernstoff, Joseph Clark, Michael B. Atkins, Howard Kaufman, Jeffrey Sosman, Jeffrey Weber, David F. McDermott
Poster Presentation:
Date and Time: Friday, November 11 12:15 – 1:30 p.m.; Friday, November 11 6:15 – 7:30 p.m. EDT
Title: A test identifying advanced melanoma patients with long survival outcomes on nivolumab shows potential for selection for benefit from combination checkpoint blockade
Poster Number: 107
Authors: Jeffrey Weber, Mario Sznol, Harriet Kluger, Ruth Halaban, Heinrich Roder, Joanna Roder, Senait Asmellash, Arni Steingrimsson, Shauna Blackmon, Ryan Sullivan
Poster Presentation:
Date and Time: Saturday, November 12 12:00 p.m. – 1:00 p.m.; Saturday, November 12 6:45 – 8:00 p.m. EDT
Title: High Dose Interleukin 2 (HD IL-2) Select Trial in Melanoma: A tissue and blood collection protocol to identify predictive biomarkers of response to HD IL-2 in patients with advanced melanoma
Poster number: 444
Authors: Ryan J. Sullivan, Yujin Hoshida, Theodore Logan, Nikhil I. Khushalani, Anita Giobbie-Hurder, Kim Margolin, Johanna Roder, Rupal Bhatt, Henry Koon, Thomas Olencki, Thomas Hutson, Brendan Curti, Shauna Blackmon, James Mier, Heinrich Roder, John Stewart, Asim Amin, Marc Ernstoff, Joseph Clark, Michael B. Atkins, Howard Kaufman, Jeffrey Sosman, Sabina Signoretti, David F. McDermott
About Biodesix
Biodesix® is a molecular diagnostics company advancing the development of innovative blood tests in oncology to enable precision medicine. Biodesix discovers, develops and commercializes multivariate protein and genomic diagnostic blood tests, including the GeneStrat® and VeriStrat® tests, that deliver results within 72 hours. The company is changing the standard of care by providing physicians with diagnostic tests for better therapeutic guidance, more accurate prognosis and enhanced disease monitoring to improve patient outcomes. At the forefront of precision medicine, Biodesix is developing new blood tests to identify patients who may benefit from immunotherapies. In addition to developing novel diagnostics independently, the company partners with biotechnology and pharmaceutical companies to develop companion diagnostics for use with therapeutic agents.